en.Wedoany.com Reported - The MZ3 case packing and palletizing machine can integrate multiple processes in the post-packaging stage of vaccine packaging, including case packing, inkjet coding, drug supervision code labeling and association, case sealing, and palletizing, achieving fully automated material flow and effectively addressing issues such as scattered processes, poor equipment connection, and excessive manual intervention in traditional packaging lines. This equipment enables fully automated operations throughout the entire process via a programmable logic controller (PLC) and HMI touch screen.
Vaccine packaging is directly related to transportation safety, storage stability, and clinical medication safety, making it a critical aspect of quality control. Currently, many domestic small and medium-sized pharmaceutical enterprises still face challenges in their packaging lines, such as scattered processes, low automation levels, poor coordination between multiple devices, excessive manual intervention, difficulty in tracing production data, and challenges in ensuring packaging accuracy and consistency. These issues constrain production efficiency and introduce quality and compliance risks. The case packing and palletizing machine can connect to the post-packaging stage of existing vaccine packaging lines and is optimized for compact layout, energy consumption control, and operational adaptability, making it a preferred solution for upgrading packaging line automation.

Taking the MZ3 case packing and palletizing machine applied in the transformation of a vaccine packaging line at a certain enterprise as an example, its core technical parameters are shown in Table 1. The main workstations of this equipment include box feeding, box stacking, box pushing, product loading into cases, case feeding, case opening, case packing, case sealing, tape sealing, drug supervision code labeling, scanning and associating drug supervision codes, and palletizing and case output. Each workstation achieves fully automated operation through programmed coordination. Using a PLC with an HMI touch screen, the equipment enables precise adjustment of parameters and seamless connection with upstream equipment in the existing vaccine packaging line, ensuring continuous material flow.

The case packing and palletizing machine handles all post-packaging processes in the vaccine packaging line. The process flow is as follows: box feeding station (connecting to the upstream cartoning machine) → box stacking station (stacking medicine boxes according to packaging requirements) → box pushing station (precisely pushing medicine boxes to the case packing station) → product loading into cases station → case feeding station (automatically feeding blank outer cartons) → case opening station (automatically forming outer cartons) → case packing station (precisely loading medicine box bundles into cases) → case sealing station → tape sealing station (meeting vaccine packaging requirements) → drug supervision code labeling and association station (automatically applying vaccine drug supervision code labels and automatically rejecting non-conforming products) → strapping station (securing cartons with straps) → palletizing and case output station (palletizing finished cartons according to vaccine warehousing requirements). The equipment achieves coordinated control of all workstations via the PLC.
For the MZ3 case packing and palletizing machine, the "MZ3 Case Packing and Palletizing Machine Usage and Cleaning SOP" has been compiled, covering the entire process of startup, operation, shutdown, cleaning, and fault handling. For example, before startup, it is necessary to check that the compressed air pressure reaches 0.6–0.8 MPa and confirm that the main power supply and safety devices are normal. Based on application practice, common faults during equipment operation, their causes, and rapid troubleshooting methods have been summarized, along with target handling times for each fault, as shown in Table 2.

Daily maintenance of the equipment follows the GMP principles of cleanliness, preventive maintenance, and traceability. After production, comprehensive cleaning and component inspection of the equipment must be carried out, including checking the synchronous belts, suction cups, and spherical rod ends of the box-gripping robot and palletizing robot for wear, inspecting the sealing of the case-opening suction cups, lubricating mechanical components, cleaning dust and material residues inside the strapping machine and at each workstation, and checking the tightness of electrical system connections.
The core application value of the case packing and palletizing machine lies in the integrated optimization of the process flow, which can comprehensively improve the operational level of the vaccine packaging line in terms of production efficiency, quality control, and compliance management. Through the PLC centralized control system, the equipment integrates multiple processes into a smooth and efficient automated production line, eliminating production losses caused by low manual handling efficiency and poor equipment coordination. In terms of quality control, relying on automated operation and high-precision control, manual intervention in production operations is significantly reduced. The secondary and tertiary association of drug supervision codes is completed through automatic scanning, reducing the risk of association errors caused by human factors. The equipment design complies with GMP standards and features comprehensive data recording functions, enabling full-process traceability and reducing compliance management risks.
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