South Korea's First Animal Radiopharmaceutical Approved for the Treatment of Feline Hyperthyroidism
en.Wedoany.com Reported - The Korea Atomic Energy Research Institute announced on September 10 that "Thyrokitty Injection (I-131)," a radiopharmaceutical developed by Dr. Lim Jae-cheong's research team for the treatment of feline hyperthyroidism, has obtained an animal drug manufacturing license issued by the Animal and Plant Quarantine Agency of South Korea.
This is South Korea's first animal radiopharmaceutical to receive final product approval, marking the transition of related technologies—previously mainly at the R&D stage—into clinical therapeutic applications for pets.
Feline hyperthyroidism is a common endocrine disease in older cats, primarily characterized by excessive secretion of thyroid hormones. According to reports, approximately 10% of cats aged 10 and above may suffer from this disease. Traditional treatment methods usually require long-term daily oral medication to regulate thyroid hormone levels.
Thyrokitty Injection treats the condition by leveraging the physiological property of the thyroid to absorb iodine. After injection, radioactive iodine-131 accumulates in thyroid tissue and acts on abnormal tissue. Compared with long-term oral administration, this therapy requires only a single dose, reducing the inconvenience of continuous medication.
In clinical trials conducted at the Chungbuk National University Animal Medical Center, the treatment success rate of a single dose of Thyrokitty reached 94.2%, higher than the 56.3% treatment success rate at week 4 of existing oral therapies. The research team also stated that regarding iatrogenic hypothyroidism, a treatment-related side effect, the incidence rate was 43.8% for existing therapies and 5.9% for Thyrokitty; no liver damage or abnormal blood cell production was observed in the trials.
A person in charge of the research team said that radiation technology has advanced from the R&D stage to practical therapeutic applications for pets. The follow-up plan will start with formal commercial supply in South Korea and promote the export of related technologies to animal pharmaceutical markets in Asia, including China and Japan.
