en.Wedoany.com Reported - Packaging machinery supplier Romaco will attend this year's Interpack exhibition, debuting the Maximus 400 tablet coater and presenting the VENTILUS Lab fluid bed system designed for laboratory work.
This automated coater can handle constantly changing conditions during the tablet coating process. For combination drugs containing metformin, tablets are often too large to be pressed into bilayer tablets, requiring a second layer formulation to be sprayed on to improve swallowability. Traditional methods take over 20 hours, with tablet weight and size continuously increasing. The Maximus 400 automatically adjusts the geometry and position of the baffles as the tablet bed volume grows, ensuring uniform spraying, eliminating manual adjustments, reducing the risk of operator exposure to highly active materials, and allowing batch sizes from 5% to 100% to be processed in the same coating drum.
The model is equipped with a fully automatic air distribution system that precisely directs airflow through the tablet bed via an adjustable exhaust damper. Tecpharm's PCA spray arm uses radar technology to continuously measure and adjust distance and spray angle, with a three-point support structure enhancing efficiency. The equipment can identify clogged nozzles and clean them automatically, balancing product quality, yield, and coating time.
To reduce the carbon footprint of the energy-intensive coating process, the Maximus 400 can optionally be equipped with an energy recovery unit. This utilizes a cross-flow heat exchanger in the air handling unit to recover heat from the exhaust air, reducing energy consumption by up to 50%, making it suitable for long-duration, high-power production.
The VENTILUS Lab fluid bed processor, exhibited alongside, comes from Innojet and integrates granulation, drying, and coating functions. It can process particles ranging from 10 microns to 2 millimeters, with applicable batch volumes from 0.7 to 7.0 liters. The annular ORBITER booster uniformly feeds process air into the cylindrical product container, reducing batch processing time by up to 25%. Combined with the central bottom-spray nozzle and booster plate, it significantly simplifies the process scale-up.
Users can choose between the ROTOJET nozzle and the newly developed FLEXIJET nozzle for granulation. Romaco states that its patented fluid bed components apply spray liquid with precise droplet sizes, which can reduce material consumption by 10% to 15% for controlled-release formulations and improve release profiles. The reduction in spray liquid volume also lowers power consumption and carbon dioxide emissions. The rotating SEPAJET filter system returns captured particles back into the process, minimizing product loss.
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