en.Wedoany.com Reported - Chen Lei, Vice Dean of West China Clinical Medical College of Sichuan University, Chief Physician and Professor of Neurology at West China Hospital, has been selected as a "Most Beautiful Science and Technology Worker." Inspired by the medical journey of a female epilepsy patient, she discovered that research on the diagnosis and treatment of epilepsy in women of childbearing age had long been neglected, leading to the establishment of the world's first female epilepsy diagnosis and treatment ontology database and Asia's first specialized cohort study project.

During a prenatal checkup, Chen Lei witnessed a pregnant woman with epilepsy worrying about medication and childbirth issues. However, when she searched for keywords such as "epilepsy," "women of childbearing age," and "pregnancy" in professional literature, she found only about 200 related papers. This result made her realize that this field, involving multiple disciplines such as neurology, obstetrics and gynecology, reproductive endocrinology, and medication use, had long been overlooked by the academic community.

Using her maternity leave, Chen Lei wrote over 100,000 words of knowledge on pregnancy for epilepsy patients, covering topics such as rational medication use and healthy childbirth, and submitted it to People's Medical Publishing House. After publication, this book became the world's first professional book on female epilepsy. Subsequently, she also authored "Perinatal Neurological Disorders," incorporated research findings on the diagnosis and treatment of female epilepsy in China into the "International Training Course on Female Epilepsy," and published a popular science book titled "You Can Also Be a Mother: A Pregnancy Guide for Women with Epilepsy."

Chen Lei also led her team to conduct research on the impact of epilepsy medications on breast milk. By collecting postpartum breast milk samples from patients for drug concentration testing, they accumulated a large amount of data, ultimately proving that the concentration of epilepsy drugs in breast milk is extremely low and does not affect infant health during breastfeeding. Based on this, she established the world's first female epilepsy diagnosis and treatment ontology database and Asia's first specialized cohort study. Currently, more than 300 hospitals participate in this cohort study, providing standardized full-lifecycle diagnosis and treatment management for women of childbearing age with epilepsy.

Under Chen Lei's efforts, the infertility rate among female epilepsy patients receiving standardized treatment dropped from 30% to 12.8%, maternal mortality decreased by half, stillbirth rate fell from 2% to 1%, and teratogenicity rate decreased from 10% to 3.6%.

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