India's Anupam Rasayan becomes world's first to produce ETFA via flow chemistry
2026-06-15 16:05
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en.Wedoany.com Reported - Custom synthesis and specialty chemicals manufacturer Anupam Rasayan India Ltd. has successfully commercialized the production of ethyl trifluoroacetate (ETFA) using its proprietary "process-by-design" continuous flow chemistry platform. This makes the company the first in the world to produce ETFA on a commercial scale using flow chemistry technology.

ETFA is an important fluorinated chemical intermediate widely used as a reagent and building block in the synthesis of organofluorine compounds. These fluorine-based compounds play a critical role in pharmaceuticals and life sciences, advanced materials, specialty chemicals, and high-performance applications, enhancing product stability, efficiency, and performance. The global addressable market for ETFA is estimated to be approximately $500 million to $600 million.

Through its advanced continuous flow chemistry platform, Anupam Rasayan has developed a manufacturing method that overcomes several limitations of traditional batch processes. This process achieves improved reaction control and higher process safety, greater consistency and product quality reproducibility, rapid scale-up from development to commercial production, higher operational efficiency and resource utilization, and reduced environmental impact through optimized processes. This technological pathway enables the company to manufacture complex fluorinated molecules more efficiently and meet evolving customer demands.

Anupam Rasayan Managing Director Anand Desai stated that the commercialization of ETFA through the continuous flow chemistry platform is a significant milestone in the company's innovation journey, demonstrating its technical expertise in complex fluorinated chemistry and its ability to develop and scale differentiated manufacturing solutions. He noted that innovation remains central to the company's growth strategy, and it will continue to invest in advanced process technologies, R&D capabilities, and sustainable manufacturing practices.

The commercial production of ETFA via flow chemistry further solidifies Anupam Rasayan's market position as an innovation-driven specialty chemicals company. According to the press release, the company is combining advanced engineering, process innovation, and sustainable manufacturing practices to create value for customers and contribute to the evolution of next-generation chemical production.

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