en.Wedoany.com Reported - German chemical company BASF recently introduced two skin rejuvenation ingredients, NeoHelix Regenerate and SkinNexus Collag3n, which utilize biotechnology to achieve precise repair and long-term maintenance of skin structure.

BASF is a German chemical enterprise, and its Beauty Care Solutions business holds a significant position in the global market. According to publicly available information, the company has long focused on the research and development of chemical materials and possesses technological expertise in the field of active ingredients. The development of these new ingredients is a result of its collaboration with external innovative forces.

NeoHelix Regenerate is a precision peptide that targets damaged collagen and triggers adaptive renewal. In clinical trials involving women aged 60-70, damaged collagen was reduced by 41% and hyaluronic acid levels increased by 65% after 56 days. In vivo studies showed improvements in skin thickness, firmness, and forehead wrinkles, with the peptide outperforming benchmark ingredients across all metrics.

SkinNexus Collag3n, on the other hand, is produced through yeast fermentation to create bio-identical collagen type III fragments, aiming to strengthen the overall collagen network of the skin. In a 3D dermal model, it supported a 48% increase in collagen I, 82% in collagen III, and 71% in collagen V. Clinical trials with women aged 53-70 indicated improved skin firmness and reduced sagging after just four weeks, outperforming a benchmark ingredient at ten times the concentration.

The application validation for these two ingredients covers clinical trials and 3D model testing, making them suitable for skin structure repair scenarios. Their development leveraged the SAION AI platform for computational optimization, accelerating the biological discovery process.

Through collaborations with 3Helix and Bota Biosciences, BASF has shifted from traditional collagen support to multi-faceted renewal and maintenance, aligning with its strategic positioning in the beauty care sector. Compared to competitors, this approach emphasizes synergy with the skin's own biological mechanisms.

In terms of technological maturity, NeoHelix Regenerate and SkinNexus Collag3n have been validated through clinical trials, with clear prospects for industrialization. This may drive the cosmetics industry towards biotechnology-driven active ingredients, reducing reliance on traditional synthetic materials.

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